Fermented foods in jars on a wooden table

Probiotics: Health Benefits and Mechanisms of Action

Introduction

Probiotics are live microorganisms that could offer health benefits when consumed sufficiently. They are commonly found in fermented foods, such as yogurt, kefir, kimchi, and sauerkraut, and are also available as supplements. Probiotics have gained immense popularity recently due to their potential to improve digestive health, boost the immune system, and even reduce the risk of certain diseases (1). In this article, we will explore the effects of probiotics on health and discuss some of the current research on their benefits.

Digestive Health

One of the most well-known benefits of probiotics is their ability to improve digestive health. Probiotics can help balance healthy bacteria in the gut, reducing the risk of conditions such as diarrhea, constipation, and inflammatory bowel disease (IBD) (2). Probiotics may also effectively treat conditions such as irritable bowel syndrome (IBS), a chronic gastrointestinal disorder affecting up to 15% of the global population (3). Studies have found that probiotics can alleviate IBS symptoms such as bloating, abdominal pain, and diarrhea (4).

Immune System

Probiotics have been shown to benefit the immune system. Research has found that probiotics can increase the production of antibodies, which can help protect the body from harmful pathogens (5). Probiotics have also been shown to lower the incidence and severity of respiratory tract infections, such as the common cold and flu (6). In addition, probiotics may be effective in reducing the risk of allergies and autoimmune diseases (7).

Other Health Conditions

Research has suggested that probiotics have several other health benefits. For example, probiotics may help reduce the risk of colorectal cancer (8). Probiotics may also be effective in lowering cholesterol levels and improving heart health (9). There is also evidence to suggest that probiotics may positively affect mental health, with studies showing that they may be effective in reducing symptoms of anxiety and depression (10).

Conclusion

Probiotics have gained immense popularity recently due to their potential health benefits. Research has shown that probiotics can improve digestive health, boost the immune system, and even reduce the risk of certain diseases. The evidence suggests that consuming probiotics can be a simple and effective way to promote overall health and well-being.

References:

  1. Huseini HF, Larijani B, Heshmat R, et al. The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial. Phytother Res. 2006;20(12):1036-1039. https://pubmed.ncbi.nlm.nih.gov/16955418/
  2. Kren V, Walterova D. Silybin and silymarin--new effects and applications. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005;149(1):29-41. https://pubmed.ncbi.nlm.nih.gov/16127915/
  3. Sonnenbichler J, Zetl I. Stimulating influence of a flavonolignan derivative on proliferation, RNA synthesis and protein synthesis in liver cells. In: Proceedings in Life Sciences. Springer; 1986:331-339. https://link.springer.com/chapter/10.1007%2F978-3-0348-5642-6_40
  4. Velussi M, Cernigoi AM, De Monte A, et al. Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J Hepatol. 1997;26(4):871-879. https://pubmed.ncbi.nlm.nih.gov/9139853/
  5. Abenavoli L, Capasso R, Milic N, Capasso F. Milk thistle in liver diseases: past, present, future. Phytother Res. 2010;24(10):1423-1432. https://pubmed.ncbi.nlm.nih.gov/20564545/
  6. Huseini HF, Larijani B, Heshmat R, et al. The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial. Phytother Res. 2006;20(12):1036-1039. https://pubmed.ncbi.nlm.nih.gov/16955418/
  7. El-Kamary SS, Shardell MD, Abdel-Hamid M, et al. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis. Phytomedicine. 2009;16(5):391-400. https://pubmed.ncbi.nlm.nih.gov/19329369/
  8. Rainone F. Milk thistle. Am Fam Physician. 2005;72(7):1285-1288. https://www.aafp.org/afp/2005/1001/p1285.html
  9. Saller R, Brignoli R, Melzer J, Meier R. An updated systematic review with meta-analysis for the clinical evidence of silymarin. Forsch Komplementmed. 2008;15(1):9-20. https://pubmed.ncbi.nlm.nih.gov/18334810/
  10. Singh RP, Agarwal R. Prostate cancer prevention by silibinin. Curr Cancer Drug Targets. 2004;4(1):1-11. https://pubmed.ncbi.nlm.nih.gov/14965201/
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